The Applied Nuclear Science Instrumentation Laboratory (ANSIL) was established in the new Nuclear Engineering Building in April 2017. This facility features approximately 1000 ft2 of quality space and supports the development of advanced instrumentation for a wide range of projects in ANSG. Some examples of current research in ANSIL include the development of novel neutron and antineutrino detectors and detection methodologies for applications in nuclear security, nonproliferation, nuclear power, and fundamental scientific research.